This Saturday England will play Italy at Twickenham. England have a huge advantage this year with 4/5 games being played at home. Italy will likely come to play being a sure underdog in this contest.
Scotland will play Wales at Murrayfield on the same day. This will be a huge test for Wales, they have lost Stephen Jones due to injury and well their record is less than glamorous.
On Sunday Ireland play France at Aviva Stadium. I think this will be the best match of the weekend. I really don't know who will reign supreme at the end of this test.